top of page
We Accept ALL Major Insurance Plans Including Medicare & Medicaid Plans! Call Now 212-540-3801!

10 Medications You Should Think Twice Before Mixing with Alcohol

When it comes to mixing medications with alcohol, it is crucial to be cautious. While having a drink might seem harmless, some medications can cause serious interactions with alcohol. Whether you’re treating a chronic illness or simply trying to soothe a cold, knowing how your medications interact with alcohol is vital for your well-being. Here’s a useful guide to ten types of medications that should ideally never be mixed with alcohol.


1. Antidepressants


Antidepressants like selective serotonin reuptake inhibitors (SSRIs), including popular options such as Lexapro and Zoloft, can lead to dangerous side effects when combined with alcohol. Drinking can intensify feelings of depression, negatively impacting mental health. A study showed that 80% of individuals on SSRIs reported worsening symptoms after consuming alcohol. If you’re on Lexapro and considering a cocktail, it’s time to rethink that choice.

Examples of SSRIs

  • Lexapro (Escitalopram)

  • Zoloft (Sertraline)

  • Prozac (Fluoxetine)

  • Paxil (Paroxetine)

  • Celexa (Citalopram)

Close-up view of a bottle of Lexapro on a wooden table
Generic Lexapro (escitalopram) tablets.

2. Painkillers


Mixing painkillers, particularly opioids like oxycodone or hydrocodone, with alcohol can create serious health risks. Both substances act as depressants, intensifying sedation and increasing the chance of respiratory failure. According to the CDC, opioids contributed to over 70,000 overdose deaths in 2019, highlighting the dangers of such combinations. If you're managing pain and have been prescribed these medications, avoid mixing them with any alcohol.

Examples of Painkillers to Avoid Mixing with Alcohol

  • Oxycodone

  • Hydrocodone

  • Codeine

  • Fentanyl

  • Morphine


3. Blood Pressure Medications


Certain blood pressure medications, such as beta-blockers and diuretics, can be negatively affected by alcohol consumption. Drinking alcohol may lower the effectiveness of these drugs, leading to dangerous spikes or drops in blood pressure. Research indicates that patients on beta-blockers who drank heavily experienced a 50% increased risk of adverse events. Talk to your healthcare provider about your drinking habits if you're on these medications.

Examples of Blood Pressure Medications Affected by Alcohol

  • Beta-blockers

  • Diuretics

  • ACE inhibitors

  • Angiotensin II receptor blockers

  • Calcium channel blockers


4. Sleep Aids


Many sleep medications, especially benzodiazepines like Ambien, can dramatically increase the sedative effects of alcohol. This mixture can cause extreme drowsiness, reduced coordination, and a higher risk of accidents. A study found that 60% of people taking benzodiazepines reported significant impairment after drinking alcohol. If you rely on sleeping pills, steering clear of alcohol is essential for your safety.

Examples of Sleep Medications and Their Interactions with Alcohol

  • Ambien (Zolpidem)

  • Ativan (Lorazepam)

  • Valium (Diazepam)

  • Xanax (Alprazolam)

  • Restoril (Temazepam)

  • Halcion (Triazolam)


High angle view of an alarm clock and a bottle of sleep aids
Alarm clock beside sleep aid medication.

5. Cholesterol Medications


Cholesterol medications, particularly statins like atorvastatin, can have adverse effects when mixed with alcohol. While moderate drinking might be fine for some, heavy alcohol use can lead to severe liver damage. Statistics reveal that heavy drinkers are at a 30% higher risk for liver-related complications when taking statins. Be mindful of your alcohol intake to avoid these potential pitfalls.

Examples of Potential Adverse Effects of Mixing Cholesterol Medications with Alcohol

  • Increased risk of liver damage

  • Heightened likelihood of muscle pain and weakness

  • Potential for elevated blood sugar levels

  • Greater chance of gastrointestinal issues

  • Increased risk of drug interactions


6. Diabetes Medications


If you are taking diabetes medications, such as insulin or sulfonylureas, tread carefully with alcohol. Drinking can lead to unpredictable fluctuations in blood sugar levels, potentially causing harmful highs or lows. According to research, over 40% of individuals with diabetes experienced dangerously low blood sugar levels after consuming alcohol. Monitor your blood glucose closely if drinking is on the agenda.

Examples of Diabetes Medications

  • Insulin

  • Sulfonylureas (e.g., glipizide, glyburide)

  • Metformin

  • DPP-4 inhibitors (e.g., sitagliptin)

  • SGLT2 inhibitors (e.g., canagliflozin)

  • GLP-1 receptor agonists (e.g., liraglutide)


7. Asthma Medications


Some asthma medications, particularly corticosteroids like prednisolone, can have adverse reactions when combined with alcohol. Though alcohol may not directly reduce their effectiveness, it can heighten side effects such as dizziness and exacerbated respiratory symptoms. To avoid complications, it is essential to discuss your alcohol consumption with your doctor if you manage asthma.

Examples of Adverse Reactions from Combining Asthma Medications with Alcohol

  • Dizziness and lightheadedness

  • Increased respiratory symptoms such as wheezing or shortness of breath

  • Heightened risk of gastrointestinal issues

  • Potential for impaired coordination

  • Increased sedation or drowsiness


8. Antibiotics


Not all antibiotics mix well with alcohol. For instance, metronidazole can trigger severe reactions, including nausea, vomiting, and abdominal pain. The FDA warns that combining this antibiotic and alcohol can lead to alarming symptoms. Always consult your healthcare provider or pharmacist about alcohol interactions when prescribed antibiotics to stay safe and healthy.

Examples of Antibiotics That Do Not Mix Well with Alcohol

  • Metronidazole - can cause severe reactions such as nausea and vomiting

  • Tinidazole - may lead to similar reactions as metronidazole

  • Disulfiram (used for treating alcohol dependence) - can cause unpleasant effects when alcohol is consumed

  • Cephalosporins - certain types may cause a reaction similar to disulfiram

  • Chloramphenicol - can have adverse effects when mixed with alcohol


9. Antihistamines


Many over-the-counter antihistamines can cause drowsiness, which can be enhanced by alcohol. Not only does this increase the risk of feeling overly sleepy, but it can also impair your ability to function, putting you at risk for accidents. If you plan on going out while taking these medications, moderate your alcohol consumption to stay safe.

Examples of Over-the-Counter Antihistamines

  • Diphenhydramine (Benadryl)

  • Chlorpheniramine (Chlor-Trimeton)

  • Dimenhydrinate (Dramamine)

  • Meclizine (Antivert)

  • Promethazine (Phenergan)


10. Anticonvulsants


For those taking anticonvulsants, the combination with alcohol can be particularly dangerous. Alcohol can hinder the effectiveness of medications like phenytoin and increase the risk of seizures. A study shows that individuals on anticonvulsants who consumed alcohol were 6 times more likely to experience seizure activity. It’s crucial to consult your healthcare provider regarding alcohol use while on these medications.

Examples of Anticonvulsants Affected by Alcohol

  • Phenytoin

  • Carbamazepine

  • Valproate

  • Lamotrigine

  • Topiramate

  • Levetiracetam



Understanding Medication and Alcohol Interactions

Navigating the relationship between medications and alcohol can be complex. Each medication comes with unique interactions with alcohol, making it essential to read labels and discuss any concerns with your healthcare provider. By knowing which medications to avoid when drinking, you can safeguard your health and reduce the risk of harmful side effects. Always prioritize your well-being. If you’re unsure, it’s wise to skip the drink. Cheers to a healthier you!


How EasyMeds Pharmacy Can Help

At EasyMeds Pharmacy, we understand the importance of managing your medications safely. Here’s how we can assist you:

  • Medication Reviews: Our pharmacists can review your current medications and inform you about any potential interactions with alcohol.

  • Consultation Services: We offer personalized consultations to discuss your specific health needs and answer any questions you may have regarding alcohol and your medications.

  • Educational Resources: EasyMeds Pharmacy provides educational materials that detail the effects of alcohol on various medications, helping you make informed choices.

  • Supportive Environment: Our team is dedicated to creating a supportive environment where you can feel comfortable discussing your health concerns.

With EasyMeds Pharmacy by your side, you can navigate your medication regimen with confidence and prioritize your health effectively.

Comments


Your Pharmacy, Simplified & Supported

At EasyMeds Pharmacy, we believe getting your medications should be easy, personal, and always focused on you.

Sorting Medicine

Prescriber Info

EasyMeds Pharmacy / 3801 Broadway Rx LLC

NPI: 1124833942

3801 Broadway, New York, NY 10032

Ph: 212-540-3801

Fax: 212-540-3802

IMG_7093.png
bottom of page